明天, 今天, 昨天(ghostneuron)

September 25, 2007

Mathmatics is beautiful

Filed under: Biology, Neuroscience

I finshed reading this paper today and get excited with the math model. It’s really simple as I finally understood it all, which is just basic calculus. And the model is still a simple one with only a few parameters, calcium, NFAT, DSCR1, DYRK1A. It makes my rusted brain from biology shinned again for mathmatical thinking. And it encourage me to rethinking my grant application on APP and S100 interaction. I am on the right way, judged by intuition, which is always right for me.

 

Occam’s razor

Filed under: Biology

I met this word when watching House today, and looked up in the wikipedia, which give out a long long discussion. It’s  so popular a concept, that it ’s used in almost every field.

I lose my patience and become irrated sometimes, which is bad for research. I need to calm down and keep my solitude for some extant. Simpler, concicer, parsimonier are always my preference…..

September 20, 2007

Dr. House

Filed under: Movies

Dr. House is a miracle, a maverick medical genius. I am infatuated with a TV series recently, and boght all the DVDs for 3 seasons. It’s witty and kowlegeable and I also learn microbiology by this way, because most cases are infectious disease like Naegleria, a parasite infection; with long names, such as Erdheim-Chester syndrome,  or rare case like gold poison…but there are also mistakes of course, like this one catched by fans in wikipedia:

  • Naegleria fowleri was featured on the TV show House, on season 2, episodes 20-21. The writers got the most dramatic symptom wrong. Both characters developed cortical blindness, a condition affecting the occipital lobes where the patient thinks he can see but really can not. This is not consistent with Naegleria fowleri, whose initial symptoms are "alteration in taste (ageusia) or smell (parosmia)".[2]

This guy is witty, humorous and a very good doctor, but different from others, a jerk, a eccentric person, but liked by every one.

Looking forward to the season 4 … 

September 18, 2007

Medicine and calculus

Filed under: Biology

found some useful web sites for Dian Dian, an example, http://www.boomer.org/c/p2/syllabus.html, a good model, http://findarticles.com/p/articles/mi_qa3997/is_200209/ai_n9094550/print, a library, http://mathforum.org/library/topics/medicine/
And interestingly, in medicine, Calculus is a disease, kidney stone; while the origin of mathmatical branch might be from the counting stones to calculate.

September 17, 2007

The food chain

Filed under: Essays

今天看到一则新闻说,美国把工业垃圾卖给中国,而中国用这些垃圾原料制成垃圾产品又卖给美国。真是有趣啊!所以全球化时代,大家都互相制约,还是和气生财的好。就像生物界的食物链,不管是位于顶端,还是位于底端,都是一个循环,一物降一物,能量守恒吗。不过大家还是都喜欢做老虎,暂时的优势即使能维持几十年也是很爽的,何况如果基因传不下去,就会永远在这个世界消失了(尽管还可以以其他的分子存在, 不知道感觉如何),连蚂蚁都做不成了。。。生命,人类社会,国家这有魔力的怪物!小可爱也是这生命世界里的一颗奇葩, 也在生物链中吃与被吃, 也一样留恋生命, 即使有时很不开心….当然了,我也不例外, 所以说生命有趣呢, 连微积分都能用到生物的增长上来……

星期一的哈佛广场很冷清,音乐家已都走了,连那个拉京胡的老头都转移阵地了,现在他躲在Park street的地铁车站里,大概是音响效果会好一点吧;只有那个做喷画的画家还在努力工作,耳边响着节奏欢快的南美音乐。。。霓虹灯的朦胧在凉凉的秋风里闪烁,象哭泣的幽灵;沿街的店铺都已打烊,偶尔见到一个流浪汉沿街逡巡着。。。黑黑的夜空里有一弯月牙,查理斯河也静静的,黑漆漆的,除了远处桥墩上的灯发出一点微弱的光来,看似寂寥的冬天已然开始了它的侵袭,尽管还是在落叶的季节。。。今天我依然游了500米,自由泳四百米,蛙泳一百米,我同时加快了手臂的抡速和双脚的海豚摆速,似乎速度有所提高,而且也不是很累,还能坚持50米。。。

Lost in diary

Filed under: Essays

今天偶然翻了翻大学时期的日记, 十多年前的, 看着自己幼稚的, 单纯的, 挣扎的,可爱的记录,感慨时光飞逝, 我已经老了, 也有对过去年轻生活的怀念…..当年记录的时候没有什么感觉, 只是我不爱跟人交流,便把思想写在日记里. 当有了时间的距离, 这东西变得那么珍贵, 它让我回忆起好多事情, 栩栩如生,恍如昨日….好多东西变了, 我的文字风格还没变, 我的理想追求还没变, 我还是那么单纯,执着, 也还是那么刚愎自用, 自我中心……

September 16, 2007

Father’s story

Filed under: Essays

今天读到一篇纽约客上的小说,"Mr.Bones" by Paul Theraux, 是以小孩子的视角"回忆" 父亲的故事. 刻画了一个充满爱心的平凡, 乐观,幽默的父亲形象, 是篇很不错的小说. 摘录几个片断:

 “I lost a child two years ago,” she said, as though threatening to lose this one, too. Dad said, “It’s going to be fine.” “How would you know?” He smiled; he had no reply. As a sort of penance, he washed the dishes, calling out, “Who’s going to dry for me?,” and, because of the tension, each of us said, “I’ll do it!,” and pushed around trying to be helpful.
Choir practice was more than a form of devotion, an expression of piety; it was a spiritual duty. Dad always went alone, and he always came back happy. His happiness wasn’t audible in anything he said, but his mood was improved—you could tell by his movements, his breathing, the way he listened, with a different sort of smile, a relaxed posture.
After that, he went over to Fred and said, “What are you going to do for Mr. Bones?” “College,” Fred said, blinking fiercely. “Know the difference between a college professor and a railway conductor?” “No.” “No what?” “No, Mr. Bones.” “One trains minds and the other minds trains. Which one do you want to be?” “College  professor, Mr. Bones.”

他的父亲因为要演小丑而在家里练习, 结果调节了家里的气氛, 艰苦的生活也变得有意思起来;但一旦演出结束, 生活似乎又重归枯燥, 他的智慧也重新掩藏起来. 这是惰性呢还是无奈? 我的父亲是个严厉的人, 从来都是居高临下地跟我说话的, 所以我从小就很怕他, 不知道怎么跟他接近, 这也影响我成年后的生活, 还是不太会跟人主动接近. 我母亲总是借一切机会叫我和他接近,叫他吃饭,跟他去单位之类, 但我从来都是战战兢兢, 很打怵…父亲跟我的话题从来都是学习功课之类的, 以至于后来我以作书呆子为自豪. 他唯一以我自豪的大概是我的记忆力. 我把家里书架上的历史书翻了几遍, 对于中国历史都是耳熟能详了;所以外人来时, 他也会借机炫耀一番. 其他的事情,我是很笨拙的, 他吩咐我帮忙我总是不能理解他的用意,以至经常让他大发雷霆. 或者是他的表达不清, 或者是我的理解迟钝, 或者两者均有. 有一次他的一个下属给他从北京打长途要他记录一些东西, 他就顺势叫我做笔录. 我匆忙找来纸笔, 只听他断断续续地喊话, 似乎是对着电话, 我以为还没有开始, 但他突然问我记录下来了吗, 我说还没记. 他恼火地抢过笔又让对方重复了一遍….我的父亲总是愁眉苦脸的, 很难见到他高兴, 我记得当时有个相声叫"老烦", 就觉着象他, 什么事情都烦,不管大小. 所以我很难想起他温暖的一面, 因为那总是掩藏的很深的, 似乎不如此就不能体现他的威严.  直到我上大学以后,  父亲似乎和善些了. 还记得入学第一天, 他带我去沈阳最好的鹿鸣春饭店吃饺子的时刻,  他还跟邻桌的一位食客聊了半天,  鲜见他如此高兴过. 之后又到沈阳联营公司买洗脸盆, 他说, " 我儿子考上医大了, 要买个质量好的,可以用五年的." 一个漂亮的女售货员帮我挑了个非常雅致的烫花脸盆. 父亲少有地说了些奉承话, "看阿姨多会挑,还不谢谢阿姨"…… 后来我出国了, 父亲老了, 病了,  话也更少了. 我每次回国时, 他都高兴地象个小孩, 我心里多是爱惜, 已经没了怨恨. 他去世两年前, 我最后陪他去浴室洗澡, 看着他枯瘦的身体, 我心里很是难受, 人生如此匆匆….十多年前, 我的爷爷奶奶去世时, 父亲还是精神矍铄, 如今却是风烛残年了….老弱, 死亡是如此之近.

September 11, 2007

Tired and tired

Filed under: Poems, Essays

Life is hard now, for my trying to do two things at the same time, both are difficult tasks. My Benming Nian didn’t bring any luck to my work yet, no experiment works, I am almost out of patience, wola…there are many reasons, but lack of studies may be most important. I am also preparing the exam for step 1, for which I still spent little time on it. I’m not young enough to manage two things well at the same time, but I will not give up either, for no pain no gain.

Just talked to Dian Dian about the working life, sometimes it’s so difficult to overcome obstacles like climbing a mountains, thinking of giving up for the peaks….but I never gave up any peak I climbed before, why should I now?   Be stronger, remember King Arthur’s story, in which he saw a spider repeat to weave its net for seven times after it was broken by the wind for seven times.

I feel better now for I am with you, and we encourage each other whenever we are weak or lost; we can overcome many obstacles. Though life is hard sometimes, it’s also entertainment, with happiness and good memories and dreams….

If we spend lots of time on work, there is little left for leisure, for literature, for poets, for movies….and only with you do I remember to pull myself out of the deep water to have a fresh breath, enjoy some culture and philosophy, most important to write some notes for little red flowers….how many?

 Une rose seule, c’est toutes les roses


一朵玫瑰,就是所有的玫瑰
与她自身:不可替代的
完美,这甜蜜的词汇
被事物本身所包围。

没有她永不知如何说
我们的希望又为何物,
而那些温柔的间断,
在持续的出发程途。

何家炜译里尔克诗
Une rose seule, c’est toutes les roses
et celle-ci: l’irremplaçable,
le parfait, le souple vocable
encadré par le texte des choses.

Comment jamais dire sans elle
ce que furent nos espérances,
et les tendres intermittences,
dans la partance continuelle.

September 5, 2007

Fight between nucleusl and mitochondria

Filed under: Biology

今天中午去听著名华人生物学家王晓东院士的报告,他对于细胞凋亡机制的探索和关于细胞器进化的思考非常有趣。几亿年前,细菌侵入真核细胞,就彼此开始了战争,此消彼长,都有自己的攻击和防卫武器——蛋白质分子;最终细菌与细胞达成平衡,长期定居于其内,彼此互利互惠,才有了线粒体这个呼吸器官。男女两性的战争也是如此,所以家庭才是稳定的传代的载体。。。

 

The Labour Day

Filed under: Travel, Poems

从东北到西南,我在天上划了一道弧线,在月圆之夜,坠落于欢乐谷的伊甸园,热浪掸掉我身上的寒气,温情熔化了我的锋芒。。。这里是红人的故乡,遍地是棕榈树和仙人掌,还有奇异的小花,灌木,在列日下的红土里静静生长。。。美洲豹,响尾蛇,黑寡妇毒蜘蛛,八哥和乌龟,唯独不见Jackrabbit,这沙漠里的小可爱,它们都躲在阴凉里睡觉。。。我们是箭和羽毛,只有绑在一起才会射得远,一重一轻,一软一硬,我们分开又重合,欢愉而青春勃发。。。这里有奇特的房屋,沙土颜色的墙壁,红瓦的屋顶,错落有致的庭院,房檐上喷出的水汽,更让人置身异境。。。我们在庭院里穿梭,试着五彩的箭囊,飘啊飘啊飘啊飘,在镜子里留下印记。。。在阴凉之夜,我们走进一处院落,里面有喷泉,橄榄树,和围桌喝茶的人群,像是我曾经过的埃及和希腊城镇,悠闲而惬意的夜晚。。。我们又走进一处酒吧,院子里满是喝酒的客人,酒保在忙碌地招待,坐在门前的绿色藤椅上,我们喝着德国的啤酒,对生活做着深思,希望产生出些思想来,也让这啤酒不至于浪费。。。






















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