AAAAA

This year’s Nobel Prize on Medicine went to stem cell research, they are Mario R. Capecchi, a Howard Hughes Medical Institute investigator at the University of Utah, Martin J. Evans at Cardiff University, and Oliver Smithies at the University of North Carolina at Chapel Hill. <The three were honored for “groundbreaking discoveries concerning embryonic stem cells and DNA recombination in mammals.” Their research has led to the development of powerful gene-targeting techniques that have provided researchers worldwide with the tools to determine the function of individual genes.>

"This technology has allowed scientists to engineer mice with conditions such as cancer, heart disease, Alzheimer’s disease, cystic fibrosis, and high blood pressure—a feat that has revolutionized the study of human disease. Gene targeting allows scientists to manipulate the genetic material of mice with amazing precision to create desired mutations in virtually any gene. By controlling the way a gene’s DNA sequence is modified, researchers can completely disrupt—or “knock out”—the function of a gene or modify its activity. Refinements in the technique over the years now enable scientists to restrict a particular genetic modification so that it affects only certain tissues or occurs only during certain stages of life."

I never heard of these three guys before, though I use the technology now; shame of me, and it’s just a field that too many people are working, which were found during 1980’s, I was still a primary school student, and go into neuroscience later. So not surprise also, but need to know now. That’s really a breakthrough techniques which accelerate all the biological research and applications. Now the genome plan is finished, and all gene knockout could be make in mice, incredible task!